What important truth do very few people agree with you on? A good answer takes the following form: "Most people believe in x, but the truth is the opposite of x." If you can identify a delusional popular belief, you can find what lies hidden behind it: the contrarian truth.
The progress can take two forms:

At the macro level, the single word for horizontal progress is globalization. The single word for vertical, 0 to 1 progress is technology.

The business version of our contrarian question is: what valuable company is nobody building? Creating value is not enough, you also need to capture some of the value you create.